By Alan H. B. Wu (auth.), Alan H. B. Wu (eds.)
Cardiac Markers is a entire, updated precis of medical info on serum cardiac markers for coronary artery ailment. This e-book experiences intimately the biochemistry, scientific importance, and analytical measurements for every marker, in addition to the benefits and boundaries of latest and proposed markers. entire descriptions of healing ways to control sufferers are awarded. additionally integrated are up to date listings of basic references and advertisement methodologies, the newest information at the pathophysiology of risky angina, and a dialogue of the recent emergency-room chest soreness facilities. someone who must understand how to ascertain, diagnose, deal with, and deal with sufferers with acute chest soreness and center assaults will locate this publication indispensable.
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One promising class of agents is represented by the platelet fibrinogen receptor antagonists: the glycoprotein IIblIIla inhibitors. These compounds block the final common pathway of platelet aggregation, thereby preventing the platelet from participating in thrombus formation and extension. ABBREVIATIONS ADP and ATP, adenosine diphosphate and adenosine triphosphate; AMI, acute myocardial infarction; AS A, acetylsalicylic acid; ATIII, antithrombin III; ~-TG, ~-throm boglobulin; CHD, coronary heart disease; ECG, electrocardiogram; ELAM-I and ICAM-I, endothelium-leukocyte and intracellular adhesion molecules-I; EDRF, endothelial-derived relaxing factor; ET-I, endothelin-l; HDL and LDL, high- and lowdensity lipoproteins; HETE, hydroxyeicosatetraenoic acid; IFN-y, interferon-y; IL-l, interleukin 1; LTB4, leukotriene B4; MCP, matrix collagenase protein; MCSF, macrophage colony-stimulating factor; MMP, matrix-degrading metalloproteinases; NO, nitrous oxide; NPH, Northwick Park Heart; Giri, Waters, and Wu PAF, platelet-activating factor; PAl, plasminogen activator inhibitors; PDGF, plateletderived growth factor; PGI-2, prostacyclin; SMC, smooth muscle cell; TF, tissue factor; TNF, tumor necrosis factor; TFPI, tissue factor pathway inhibitor; TGF-~ and FGF, transforming and fibroblast growth factors; TIMI, thrombolysis in myocardial infarction; TIMP, tissue inhibitor of metalloproteinases; t-PA, tissue plasminogen activator; tissue necrosis factor; TxA2, thromboxaneA2; VA, unstable angina; vWF, von Willebrand factor.