Biomedical Applications of Polymeric nanofibers by Sowmya Srinivasan, R. Jayakumar (auth.), Rangasamy

By Sowmya Srinivasan, R. Jayakumar (auth.), Rangasamy Jayakumar, Shantikumar Nair (eds.)

Multiscale Fibrous Scaffolds in Regenerative drugs, via Sowmya Srinivasan, R. Jayakumar, okay. P. Chennazhi, Erica J. Levorson, Antonios G. Mikos and Shantikumar V. Nair; Stem Cells and Nanostructures for complex Tissue Regeneration, by way of Molamma P. Prabhakaran, J. Venugopal, Laleh Ghasemi-Mobarakeh, Dan Kai Guorui Jin and Seeram Ramakrishna; growing Electrospun Nanofiber-Based Biomimetic Scaffolds for Bone Regeneration, through Eleni Katsanevakis, Xuejun Wen and Ning Zhang; Synthetic/Biopolymer Nanofibrous Composites as Dynamic Tissue Engineering Scaffolds, by way of J. A. Kluge and R. L. Mauck; Electrospun Fibers as Substrates for Peripheral Nerve Regeneration, through Jörg Mey, Gary Brook, Dorothée Hodde and Andreas Kriebel; hugely Aligned Polymer Nanofiber constructions: Fabrication and functions in Tissue Engineering, by means of Vince Beachley, Eleni Katsanevakis, Ning Zhang, Xuejun Wen; Electrospinning of Biocompatible Polymers and Their Potentials in Biomedical purposes, via Pitt Supaphol, Orawan Suwantong, Pakakrong Sangsanoh, Sowmya Srinivasan, Rangasamy Jayakumar and Shantikumar V. Nair; Electrospun Nanofibrous Scaffolds-Current prestige and customers in Drug supply, via M. Prabaharan, R. Jayakumar and S. V. Nair.; Biomedical purposes of Polymer/Silver Composite Nanofibers, through R. Jayakumar, M. Prabaharan, ok. T. Shalumon, ok. P. Chennazhi and S. V. Nair.-

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56 1 Introduction The basic functional units of cells and tissues are of nanoscale dimensions, and nanotechnology promises an important area of study in regenerative medicine. Cells are typically of tens of micrometers in diameter, and cellular structures such as the cytoskeletal elements and transmembrane proteins too exist in nanoscale proportions [1]. , showing the complexity of the structures present in vivo [2].

Pham QP, Sharma U, Mikos AG (2006) Biomacromolecules 7:2796 53. 0028 54. Santos MI, Tuzlakoglu K, Fuchs S, Gomes ME, Peters K, Unger RE, Piskin E, Reis RL, Kirkpatrick CJ (2008) Biomaterials 29:4306 55. Edwards SL, Church JS, Werkmeister JA, Ramshaw JAM (2009) Biomaterials 30:1725 56. Cima LG, Vacanti JP, Vacanti C, Ingber D, Mooney D, Langer RJ (1991) J Biomech Eng 113:143 57. Soliman S, Pagliari S, Rinaldi A, Forte G, Fiaccavento R, Pagliari F, Franzese O, Minieri M, Nardo PD, Licoccia S, Traversa E (2010) Acta Biomater 6:1227 58.

28 2 Strategies for Advanced Tissue Regeneration . . . . . . . . . . . . . . . . . . . . . . . 1 Osteogenesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Chondrogenesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Tendon and Ligament Tissue Engineering . . . . . . . . . . . . . . . . . . . . . . 4 Cardiac Regeneration .

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