Biological Monitoring of Exposure and the Response at the by P. M. D. Foster (auth.), Philip L. Chambers, Claire M.

By P. M. D. Foster (auth.), Philip L. Chambers, Claire M. Chambers, Helmut Greim (eds.)

This complement comprises the papers submitted at EUROTOX 88, the joint Congress of the eu Society of Toxicology and the Federation of the ecu Societies of Toxicology. The subject matter was once considered one of tracking and reading the consequences of poisonous elements within the organic reaction on the subcellular point. Mechanisms of steel carcinogenicity are mentioned in addition to the biomonitoring of chemical publicity. studies are supplied at the position of person adjustments in guy and the impression of chance evaluate. Papers seem facing the genetic keep watch over of drug metabolizing enzymes. The function of metabolism in natural particular toxicity is mentioned. info is incorporated at the toxicological influence of chemical substances interfering with the endocrine method in addition to at the results of toxicants at the immune approach. displays take care of the present prestige of danger evaluation in environmental toxicology.

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Additional info for Biological Monitoring of Exposure and the Response at the Subcellular Level to Toxic Substances: Proceedings of the European Society of Toxicology Meeting held in Munich, September 4–7, 1988

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Environ Res 34:227241 Skilleter DN (1987) Beryllium p 61-86 in Fishbein et al (eds) Genotoxic and carcinogenic metals: environmental and occupationel occurrence and exposure. Princeton Scientific Publishing CO, Princeton, USA Steinhoff D (1987) Institut für Toxikologie. Bayer AG, Wuppertal, FRG. Personal Letter Stokinger HE (1981) The metals. Antimony p 1505 In: Clayton DG, Clayton FE (eds). Patty's Industrial Hygiene and Toxicology 3rd ed, Wiley Interscience, New York Sunderman FW Jr (1977) Metal carcinogenesis p 257-297.

In view of the limited number of cases, the association of arsenic exposure with these two types of cancer is still hypothetical. Chromosomal aberrations have been found in peripherallymphocytes of copper smelter workers and in persons who had received arsenic containing drugs (Leonard and Lauwerys 1980a). g. oesophagus, bladder, liver, kidney). For a long time arsenic has been considered as a human carcinogen which was not active in rodents. However, recent studies have shown that under certain exposure conditions arsenic can induce lung cancer in hamsters (Pershagen et al 1984; Yamamato et al 1987).

Am J Pathol 50:571-603 Mur JM, Moulin JJ, Charruyer-Seinerra MP, Lafitte J (1987 a) A cohort mortality study among cobalt and sodium workers in an electrochemical plant. Am J Ind Med 11 :75-81 Mur JM, Meyer-Bisch C, Pham QT, Massin N, Moulin JJ, Cavalier C, Sadoul P (1987b) Risk of lung cancer among iron ore miners: a proportional mortality study of 1075 deceased miners in Lorraine, France. J Occup Med 29:762-768 Norseth T (1981) The carcinogenicity of chromium. Environ Health Perspect 40: 121-130 Oldiges H, Glaser U, Hochrainer D (1987) Long-term inhalation study with four different cadmium compounds in rats p.

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