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This ebook reports present study in peritoneal malignant dissemination, from its pathogenesis and molecular mechanisms to the newest medical trials. The e-book covers the necessities of perioperative intraperitoneal chemotherapy and smooth histopathological evaluate of peritoneal floor malignancy. The book’s ancient viewpoint at the unfolding of recent wisdom issues the way in which for destiny examine. participants comprise major specialists, between them the pioneers who gave start to this new period in oncology.
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From these results it can be concluded that TS-1 treatment is safe and effective as adjuvant postoperative chemotherapy for patients with P0/Cy1 status. Hyperthermic intraperitoneal perfusion chemotherapy (HIPEC) is also reported to be effective for the prevention of recurrence in patients with P0Cy1 status. After radical gastrectomy for patients with potentially curable serosa-involved gastric cancer, the peritoneal cavity was perfused with 6–8 l of heated saline at 42 degrees centigrade with 30 mg of MMC and 150 mg of CDDP for 60 min .
Landry J, Tepper JE, Wood WC, Moulton EO, Koerner F, Sullinger J (1990) Patterns of failure following curative resection of gastric carcinoma. Int J Radiat Oncol Biol Phys 19:1357–1362 30. Burke EC, Karpeh MS Jr, Conlon KC, Brennan MF (1998) Peritoneal lavage cytology in gastric cancer: an independent predictor of outcome. Ann Surg Oncol 5:411–415 31. Suzuki T, Ochiai T, Hayashi H, Nakajima K, Yasumoto A, Hishikawa E, Shimada H, Horiuchi F, Ohki S, Isono K (1999) Importance of positive peritoneal lavage cytology findings in the stage grouping of gastric cancer.
1b) Bando et al. reported that 5% (51/1001) of 1001 patients with potentially curable gastric cancer showed peritoneal free cancer cells, and the 5-year survival rate of the patients with P0 (no established macroscopic peritoneal seeding) Cy1 status was only 2% . Wu et al. reported that peritoneal free cancer cells were found in 19% of 134 patients with potentially curable serosa-involved gastric cancer . A positive cytology is significantly associated with wall invasion, histological type, infiltrating growth, and size of serosal inva- Y.