100 Years of Virology: The Birth and Growth of a Discipline by A. van Kammen (auth.), Prof. Dr. Charles H. Calisher, Prof.

By A. van Kammen (auth.), Prof. Dr. Charles H. Calisher, Prof. Dr. M. C. Horzinek (eds.)

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In 1991 the production units was separated and privatised. The insular part became the "Federal Research Centre for Virus Diseases of Animals" (the first 36 W. Wittmann president was Prof. Dr. Volker Moennig; since 1994 Prof. Dr. Thomas C. Mettenleiter) and is now to become the only location of veterinary research in this field in Germany. It is self-evident that even today one is faced with Loeffler's ideas of research on the Riems, particularly when reading: " .. " and coincidentally you are quite close to Loeffler's striving to know the causative agents (" ...

Waldmann 0, Pape J (1920) Die kunstliche Ubertragung des Maul- und Klauenseuchevirus auf das Meerschweinchen. Bed Tierarztl Wochenschr 1920: 519-520 69. Waldmann 0, Reppin K (1935) Experimentelle Untersuchungen zur aktiven Immunisierung gegen Maul- und Klauenseuche. Z Inf Krkh Haustiere 47: 283-322 70. Waldmann 0, Kobe K, Pyl G (1937) Die aktive Immunisierung der Rinder gegen Maulund Klauenseuche mittels Formolimpfstoff. Zbl Bakteriol Abt I Orig 138: 461-468 71. Waldmann 0, Pyl G, Hobohm KO, Mohlmann H (1941) Die Entwicklung des Riemser Adsorbatimpfstoffes gegen Maul- und Klauenseuche und seine Herstellung.

Herpes simplex virus (HSV) was among the few exceptions. The unequivocally infectious nature of HSV was recognised 1919 by A. Lowenstein. He demonstrated that virus retrieved from vesicles of herpes labialis produced lesions on the cornea of the rabbit [1]. E. Schneweis found that 2 serotypes of HSV, HSV-l and HSV-2, can be differentiated, which are associated with differences in the clinical manifestation of infection [2]. Whereas HSV-l predominates in infections "above the belt", HSV-2 is associated with genital disease.

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